About Help FAQ

Symbol
Name
ID

Lrp4
low density lipoprotein receptor-related protein 4
MGI:2442252

Phenotype annotations related to nervous system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Facial palsy	Difficulty walking	Cranial nerve compression	Spastic ataxia	Tetraparesis	Hyporeflexia	Gait disturbance	Delayed gross motor development
Disease(s) Associated with LRP4	Facial palsy	Difficulty walking	Cranial nerve compression	Spastic ataxia	Tetraparesis	Hyporeflexia	Gait disturbance	Delayed gross motor development
Cenani-Lenz syndactyly syndrome
congenital myasthenic syndrome 17
sclerosteosis 2

Mouse Phenotypes		nervous system phenotype	abnormal motor neuron morphology	abnormal neuromuscular synapse morphology	failure of neuromuscular synapse postsynaptic differentiation	failure of neuromuscular synapse presynaptic differentiation	abnormal phrenic nerve morphology	abnormal endplate potential	abnormal miniature endplate potential
Availability	Mouse Genotype	nervous system phenotype	abnormal motor neuron morphology	abnormal neuromuscular synapse morphology			abnormal phrenic nerve morphology	abnormal endplate potential	abnormal miniature endplate potential
	Lrp4^mitt/Lrp4^mitt
	Lrp4^mte/Lrp4^mte
	Lrp4^tm1Her/Lrp4^tm1Her
	Lrp4^tm2Her/Lrp4^tm2Her
	Lrp4^tm1.1Line/Lrp4^tm1.1Line Tg(ACTA1-cre)79Jme/0 (conditional)
	Lrp4^tm1.1Line/Lrp4^tm1.1Line Mnx1^tm4(cre)Tmj/Mnx1⁺ (conditional)	*
	Lrp4^tm1.1Line/Lrp4^tm1.1Line Mnx1^tm4(cre)Tmj/Mnx1⁺ Tg(ACTA1-cre)79Jme/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23